1.
J Indian Med Assoc
;
1986 Dec; 84(12): 376-8
Article
in English
| IMSEAR
| ID: sea-102751
Subject(s)
Adult , Drug Therapy, Combination , Ethambutol/blood , Female , Humans , Male , Middle Aged , Rifampin/therapeutic use , Tuberculosis, Pulmonary/blood
2.
Article
in English
| IMSEAR
| ID: sea-18520
3.
Indian J Physiol Pharmacol
;
1986 Jan-Mar; 30(1): 115-7
Article
in English
| IMSEAR
| ID: sea-106706
4.
Indian J Physiol Pharmacol
;
1985 Oct-Dec; 29(4): 223-6
Article
in English
| IMSEAR
| ID: sea-108417
ABSTRACT
Ethambutol (20 mg/kg) was administered orally to 10 patients of pulmonary tuberculosis for seven consecutive days at 8 a.m. after over night fast. On 7th day serum levels were measured at 2, 4, 6, 8 and 24 hr intervals and urinary excretion was estimated at 2, 4, 6 and 24 hr following ethambutol administration. Simultaneous administration of isoniazid (300 mg, orally) for next seven days to the same patients significantly raised the serum levels of ethambutol at 4, 6 and 8 hr and the cumulative per cent dose excreted was decreased significantly at 4, 6 and 24 hr. The serum levels and urinary elimination was not significantly different at 2 hr.
Subject(s)
Administration, Oral , Adult , Ethambutol/metabolism , Female , Humans , Isoniazid/metabolism , Male , Middle Aged , Tuberculosis, Pulmonary/drug therapy
5.
Article
in English
| IMSEAR
| ID: sea-89840